FIELD: medicine; pharmacology.
SUBSTANCE: invention refers to medicine, particularly to pharmacology, and can be used to eliminate or prevent epileptic convulsions. Purpose of the invention is to search for new anticonvulsants among 7-oxycoumarin derivatives. Problem is solved using synthetic compound 7-(2-Morpholino-2-oxoethoxy)-2H-chromen-2-one.
EFFECT: in experiments on animals (mice) it is proved that the compound shows anticonvulsant activity, by 100 % protecting animals from death after LD50 nicotine introduction (14 mg/kg).
1 cl, 3 tbl
Title | Year | Author | Number |
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N-SUBSTITUTED (1S,4AR,5S)-METHYL-5-[2-(2'-OXO-2',5'-DIHYDRO1-H-PYRROL-3'-YL)ETHYL]-1,4A-DIMETHYL-6-METHYLENEDECAHYDRONAPHTHALENE-1-CARBOXYLATES HAVING ANTICONVULSANT ACTIVITY | 2008 |
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Authors
Dates
2019-11-12—Published
2018-12-28—Filed