FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine and can be used for preparing a drug for relieving skeletal muscle loss or skeletal muscle function associated with amyotrophic lateral sclerosis (ALS). That is ensured by introducing levosimendan or its active metabolite (R)-N-[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl phenyl]-acetamide (II) or pharmaceutically acceptable salts. Also disclosed is a method of facilitating loss of skeletal muscle or skeletal muscle function.
EFFECT: group of inventions enables relieving loss of skeletal muscle strength or skeletal muscle function in patients with amyotrophic lateral sclerosis.
8 cl, 2 dwg, 2 ex
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---|---|---|---|
USE OF SULPHATE SALTS OF N-(3-(4-(3-(DIISOBUTYLAMINO)PROPYL)PIPERAZIN-1-YL)PROPYL)-1N-BENZO[D]IMIDAZOL-2-AMINE AND THEIR SOLVATES FOR TREATMENT OF MOTOR NEURON DISEASES AND NEUROMUSCULAR DISEASES | 2021 |
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Authors
Dates
2019-11-13—Published
2015-10-14—Filed