FIELD: pharmacology.
SUBSTANCE: invention relates to derivatives of 1,4-benzothiazepine (I)
,
as well as to pharmaceutical compositions and application.
EFFECT: new compounds are obtained that can be used to treat or prevent RyRs-associated diseases and states, namely cardiac disorders, musculoskeletal disturbances and central nervous system disturbances.
27 cl, 11 dwg, 3 tbl
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