FIELD: medicine.
SUBSTANCE: invention relates to a method for the treatment of a condition that is mediated by cystic fibrosis transmembrane conductivity regulator (hereinafter – CFTR) in a patient, including injection to a patient of a Compound (I) represented by the following structural formula:
, or its pharmaceutically acceptable salt in the amount from 150 mg to 200 mg once a day, as well as to a pharmaceutical composition intended for the treatment of a condition mediated by CFTR in a patient, including a pharmaceutically acceptable carrier or diluent and from 150 mg to 200 mg of a compound represented by the following structural formula:
, or its pharmaceutically acceptable salt.
EFFECT: obtaining compounds for the treatment of a condition mediated by CFTR.
15 cl, 4 tbl, 7 ex, 12 dwg
Title |
Year |
Author |
Number |
FORMULATIONS OF 3-(6-(1-(2,2-DIFLUOROBENZO[D][1,3]DIOXOL-5-YL)CYCLOPROPANECARBOXAMIDO)-3-METHYLPYRIDIN-2-YL)BENZONIC ACID |
2013 |
|
RU2644723C2 |
NEURO-ATTENUATING KETAMINE AND NORKETAMINE COMPOUNDS, THEIR DERIVATIVES AND THEIR PRODUCTION METHODS |
2015 |
- Landrau, Nelson
- Nivorozhkin, Alex
|
RU2771275C2 |
OLIGONUCLEOTIDES FOR MAKING CHANGE IN SEQUENCE OF TARGET RNA MOLECULE PRESENT IN LIVING CELL |
2013 |
- De Boer Deniel Anton
- Ritsema Tita
|
RU2663110C2 |
STABLE COMPOSITIONS OF ASCORBIC ACID AND METHODS OF THEIR USE |
2018 |
- Kopland, Den
- Darem, Kerolin
|
RU2799046C2 |
NEW TREATMENT |
2015 |
- Ebbott-Banner Ketarin
- Khanrakhan Dzhon
- Tomas Devid
|
RU2688191C2 |
SILICON-CONTAINING IVACAFTOR ANALOGUES |
2017 |
- Munoz, Benito
- Parks, Daniel
- Bastos, Cecilia, M.
|
RU2796112C2 |
PHARMACEUTICAL COMPOSITIONS FOR TREATING DISEASES MEDIATED BY CYSTIC FIBROSIS TRANSMEMBRANE REGULATOR CFTR |
2013 |
- Verwijs, Marinus, Jacobus
- Karkare, Radhika
- Moore, Michael, Douglas
|
RU2827711C2 |
ORGANIC COMPOUNDS |
2015 |
- Mates, Sharon
- Li, Peng
- Wennogle, Lawrence P.
- Davis, Robert
|
RU2785871C2 |
ORGANIC COMPOUNDS |
2017 |
|
RU2733975C2 |
NEW COMPOSITIONS AND METHODS |
2018 |
- Li, Peng
- Yao, Wei
- Davis, Robert
|
RU2767410C2 |