FIELD: chemistry; pharmaceutics.
SUBSTANCE: group of inventions relates to chemistry and pharmaceutics, specifically to a pharmaceutically acceptable salt of enantiomer pyrrolole, formed by methanesulphonic acid, selected from a group comprising mesylate (S)-pyrrolidol and mesylate (R)-pyrrolindole; as well as to a pharmaceutical composition for treating depression, comprising said salt together with pharmaceutically acceptable carriers, diluents or excipients.
EFFECT: group of inventions provides a novel alternative form of pyrlindole with higher rate of dissolution.
5 cl, 1 tbl, 11 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING OPTICALLY ACTIVE ENANTIOMERS OF PIRLINDOLE AND ITS SALTS | 2014 |
|
RU2666731C2 |
| (S)-PIRLINDOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR USE IN MEDICINE | 2014 |
|
RU2695647C2 |
| (R)-PIRLINDOLE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS FOR USE IN MEDICINE | 2014 |
|
RU2695607C2 |
| SYNTHESIS OF SUBSTITUTED GAMMA-CARBOLINES CONDENSED WITH A HETEROCYCLE | 2019 |
|
RU2795581C2 |
| 5-AMINO-2,4,6,7-TETRAMETHYL-2-(4-PHENYLPIPERIDINOMETHYL)-2,3- -DIHYDROBENZO-[B]-FURAN ENANTIOMER CRYSTALLINE SALTS, METHOD OF ITS SYNTHESIS, PHARMACEUTICAL COMPOSITION AND A METHOD OF LIPID PEROXIDE FORMATION INHIBITION | 1993 |
|
RU2125567C1 |
| SYNTHESIS OF CHIRALLY PURE SUBSTITUTED BENZOTHIAZOLE DIAMINES | 2008 |
|
RU2454409C2 |
| REBOXETIN PHARMACEUTICAL SALTS | 2003 |
|
RU2286341C2 |
| METHOD OF PRODUCING DEXMEDETOMIDINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | 2023 |
|
RU2824994C1 |
| METHODS OF PRODUCING OPTICALLY ACTIVE CIS-2-HYDROXYMETHYL-4-(CYTOSIN-1'-YL)-1,3-OXATHIOLANE OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | 2005 |
|
RU2430919C2 |
| METHOD OF PREPARING ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS, ENANTIOMERICALLY PURE ACID ADDITION SALT OF IMIDAZOLYL AND D-OR L-PYROGLUTAMIC ACID, AND HYDROCHLORIDE MONOHYDRATE OF ENANTIOMERICALLY PURE IMIDAZOLYL COMPOUNDS | 1996 |
|
RU2162085C2 |
