FIELD: medicine; pharmaceuticals.
SUBSTANCE: proposed group of inventions refers to medicine, particularly to neurology. Presented is a method for preventing or reducing a migraine headache in a patient and a method for preventive treatment of a migraine patient, comprising administering to a patient an anti-CGRP receptor antibody or antigen-binding fragment thereof in dose of 35 mg to 210 mg once a month. Pre-filled autoinjector or syringe for preventive treatment of migraine, including a pharmaceutical composition containing 70 or 140 mg of CGRP receptor antibody, acetate buffer, saccharose and polysorbate.
EFFECT: presented group of inventions provides effective reduction of the frequency, severity and/or duration of migraine headache in the patients having indications for this purpose without any or with minimal undesirable side effects.
28 cl, 9 dwg, 11 tbl, 5 ex
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