COMBINED THERAPY FOR CANCER TREATMENT Russian patent published in 2020 - IPC A61K39/395 A61P35/00 

Abstract RU 2731202 C2

FIELD: medicine.

SUBSTANCE: invention relates to use of a combination comprising (a) B7-H3 antibody or antigen-binding fragment thereof, wherein said B7-H3 antibody or antigen-binding fragment thereof is administered in a dose of about 1–15 mg/kg of body weight, and (b) an anti-PD-1 antibody or antigen-binding fragment thereof for treating cancer in a subject in need thereof.

EFFECT: invention provides intensified anticancer activity.

46 cl, 1 ex, 6 tbl

Similar patents RU2731202C2

Title Year Author Number
IMPROVED METHODS OF TREATING VASCULARISED MALIGNANT TUMORS 2015
  • Chi Andrew S.
RU2692248C2
SPECIFIC LINKING AGENTS AGAINST B7-H1 2010
  • Kueva, Kristof
  • Morrou, Majkl
  • Khehmmond, Skott
  • Alimzhanov Marat
  • Behbkuk, Dzhon
  • Foltts, Jan
  • Kang, Dzhaspal, Singkh
  • Sekirov, Laura
  • Bojl, Melani
  • Chodorzh, Matt'E
  • Stjuart, Ross
  • Malgru, Kehtlin Ehnn
RU2571204C2
ANTIBODY AGAINST B7-H3, ITS ANTIGEN-BINDING FRAGMENT AND THEIR MEDICAL USE 2018
  • Gu, Tszinmin
  • Van, Syaokhua
  • E, Sin
  • Yan, Lyutsin
  • Chzhan, Tin
  • Tao, Vejkan
  • Chzhan, Lyanshan
RU2765306C2
ANTIBODIES AND OTHER MOLECULES BINDING B7-H1 AND PD-1 2012
  • Langermann Solomon
  • Lyu Linda
  • Marshall Shenon
  • Yao Shen
RU2625034C2
METHODS OF TREATING CANCER USING PD-1 AXIS BINDING AND VEGF ANTAGONISTS 2013
  • Maecker Heather
  • Irving Bryan
RU2689760C2
ANTI-PD-L1 ANTIBODIES AND METHODS FOR THEIR DIAGNOSTIC USE 2015
  • Liao Zhiming
  • Kowanetz Marcin
  • Boyd Zachary
  • Koeppen Hartmut
  • Roche Patrick C.
  • Zhu Yifei
  • Vennapusa Bharathi
RU2715038C2
ANTI-B7-H3-ANTIBODY 2012
  • Takakhasi Su
  • Matsuoka Tatsudzi
  • Murakami Kendzi
  • Takizava Takesi
  • Khirotani Kendzi
  • Urano Atsusi
  • Fukuti Kejsuke
  • Yadzava Mitsukhiro
RU2668170C2
SPECIFIC BINDING AGENTS AGAINST B7-H1 2010
  • Kueva Kristof
  • Morrou Majkl
  • Khemmond Skott
  • Alimzhanov Marat
  • Bebkuk Dzhon
  • Foltts Yan
  • Kang Dzhaspal Singkh
  • Sekirov Laura
  • Bojl Melani
  • Chodorzh Matte
  • Styuart Ross
  • Malgru Ketlin Enn
RU2706200C2
ANTIBODIES TO H7CR 2013
  • Langermann Solomon
  • Lyu Linda
  • Yao Shen
  • Chen Lepin
RU2650756C2
ANTI-PD-L1 ANTIBODY AND ITS USE 2020
  • Fang, Jianmin
  • Jiang, Jing
  • Li, Shenjun
  • Zhao, Guorui
RU2783685C2

RU 2 731 202 C2

Authors

Vasselli, Dzhejms

Uigginton, Dzhon Mark

Bonvini, Etsio

Kenig, Skott

Dates

2020-08-31Published

2016-10-06Filed