FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology. Invention represents a plague, parvoviral enteritis, botulism and pseudomonosis vaccine. Associated vaccine is two-component (dry component and liquid component – solvent for dry component) and contains for one vaccination dose (1 ml): lyophilized virus-containing liquid of strain of carnivore plague virus EPMM with stabilizer – titre of not less than 102.2 TCD, suspension adsorbed on aluminum hydroxide by formaldehyde inactivated culture of carnivore parvovirus strain "Hercules" – titre to inactivation of at least 1:64 in RGA with swine erythrocytes, suspension adsorbed on aluminum hydroxide inactivated culture of carnivore parvovirus strain "Coastal" – titre to inactivation of at least 1:64 in RGA with swine red cells, botulinum adsorbed type C anatoxin from strain CI. Botulinum N 365 – activity of not less than 5–10 EC, mixed adsorbed suspension Ps. Aeruginosa strains of serotype 6 "Vazuza", 1677-08 N 63 and "Dn"-05 N 77, taken in equal proportions – 0.6 billion cells.
EFFECT: vaccine has low reactogenicity while maintaining high immunogenicity for both minks and sables.
1 cl
Title |
Year |
Author |
Number |
VACCINE "BIONOR" AGAINST PLAGUE, VIRAL ENTERITIS, BOTULISM AND PSEUDOMONOSIS IN MINKS, PLAGUE VIRUS VACCINE STRAIN ЭПММ IN CARNIVORE ANIMALS AND PARVOVIRUS VACCINE STRAIN "GERKULES" IN CARNIVORE ANIMALS |
1998 |
- Sulimov A.A.
- Kolyshkin V.M.
- Ulasov V.I.
- Birjukova T.A.
|
RU2150295C1 |
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- Kirillov L.V.
- Ulasov V.I.
- Selivanov A.V.
- Sedov N.K.
- Domskij I.A.
|
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- Sulimov A.A.
- Kolyshkin V.M.
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|
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- Poljakov E.A.
|
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|
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