VACCINE "BIOCON" AGAINST PLAGUE, PARVOVIRAL ENTERITIS, BOTULISM AND PSEUDOMONOSIS OF MINKS AND SABLES Russian patent published in 2019 - IPC C12N1/20 C12N7/00 A61K39/02 A61K39/104 A61K39/12 

Abstract RU 2708980 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to the field of biotechnology. Invention represents a plague, parvoviral enteritis, botulism and pseudomonosis vaccine. Associated vaccine is two-component (dry component and liquid component – solvent for dry component) and contains for one vaccination dose (1 ml): lyophilized virus-containing liquid of strain of carnivore plague virus EPMM with stabilizer – titre of not less than 102.2 TCD, suspension adsorbed on aluminum hydroxide by formaldehyde inactivated culture of carnivore parvovirus strain "Hercules" – titre to inactivation of at least 1:64 in RGA with swine erythrocytes, suspension adsorbed on aluminum hydroxide inactivated culture of carnivore parvovirus strain "Coastal" – titre to inactivation of at least 1:64 in RGA with swine red cells, botulinum adsorbed type C anatoxin from strain CI. Botulinum N 365 – activity of not less than 5–10 EC, mixed adsorbed suspension Ps. Aeruginosa strains of serotype 6 "Vazuza", 1677-08 N 63 and "Dn"-05 N 77, taken in equal proportions – 0.6 billion cells.

EFFECT: vaccine has low reactogenicity while maintaining high immunogenicity for both minks and sables.

1 cl

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RU 2 708 980 C1

Authors

Dates

2019-12-12Published

2018-08-10Filed