FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to ophthalmology, and is intended for prediction of unfavorable course of uveal melanoma related to tumor microenvironment. A pathological examination of the enucleated tumor microenvironment is performed in the patient with the UM. If observing mast cells, fibroblasts, suppressor cells of myeloid origin in the number of at least 6 cells of each type and presence of tumor cells in the lumen of at least one scleral emissary, unfavorable course of uveal melanoma is predicted.
EFFECT: use of the invention provides higher accuracy of determining the severity of uveal melanoma for the selection of further adequate management and treatment strategies.
1 cl, 2 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR PREDICTING THE SURVIVAL CAPACITY OF PATIENTS AFTER ENUCLEATION FOR INITIAL CHOROID MELANOMA SPREAD TO THE OPTIC DISC | 2021 |
|
RU2778965C1 |
METHOD FOR PREDICTION OF SEVERE UVEAL MELANOMA | 2019 |
|
RU2705417C1 |
METHOD FOR PREDICTION OF UNFAVORABLE COURSE OF INITIAL CHOROID MELANOMA AFTER ORGAN-PRESERVING TREATMENT, BASED ON DETERMINATION OF LEVEL OF TRANSFORMING GROWTH FACTOR TGF-β2 | 2020 |
|
RU2733577C1 |
METHOD FOR PREDICTION OF SURVIVAL RATE AFTER ENUCLEATION WITH UVEAL MELANOMA DEVELOPED TO EQUATOR | 2024 |
|
RU2822319C1 |
METHOD FOR DETECTING AN INFLAMMATORY COMPONENT THAT PROMOTES TUMOR GROWTH IN INITIAL CHOROIDAL MELANOMA | 2020 |
|
RU2748528C1 |
METHOD FOR ULTRASOUND DIAGNOSIS OF INVASION OF JUXTAPAPILLARY UVEAL MELANOMA (UM) INTO THE INTRABULBAR PART OF THE OPTIC NERVE | 2023 |
|
RU2807527C1 |
METHOD FOR PREDICTING CLINICAL FLOW OF UVEAL MELANOMA | 2001 |
|
RU2193200C1 |
METHOD PREDICTING CLINICAL COURSE OF UVEA MELANOMA BASED ON APOPTHOSIS MARKER p53 | 2002 |
|
RU2208789C1 |
METHOD FOR DIFFERENTIAL DIAGNOSIS OF INITIAL MELANOMA OF CILIOCHOROIDAL LOCALIZATION AND CHRONIC IRIDOCYCLITIS | 2019 |
|
RU2715678C1 |
METHOD FOR PREDICTION OF UNFAVOURABLE COURSE OF UVEAL MELANOMA | 2018 |
|
RU2698797C1 |
Authors
Dates
2019-12-17—Published
2019-08-26—Filed