SCALE PRODUCTION METHOD OF PRODUCING RECOMBINANT LENTIVIRAL VECTORS IN CELL CULTURE SYSTEM IN SERUM-FREE SUSPENSION Russian patent published in 2019 - IPC C12N7/02 

Abstract RU 2709678 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology. described are methods of purifying the recombinant lentiviral vector (rLV).

EFFECT: invention enables to obtain highly purified rLV vector compositions on a scale required to satisfy requirements for human gene therapy.

38 cl, 9 dwg, 1 ex

Similar patents RU2709678C2

Title Year Author Number
RECOMBINANT LENTIVIRAL VECTOR, HOST CELL TRANSDUCED WITH LENTIVIRAL VECTOR, METHODS FOR TRANSDUCTION AND USES THEREOF 2002
  • Trono Did'E
  • Viznerovich Matsej
RU2305708C2
COMPLETELY SCALABLE METHOD FOR PRODUCING rAAV BASED ON COLUMNS 2017
  • Qu, Guang
  • Oh, Younghoon
  • Lu, Lin
  • Wright, John Fraser
RU2754467C2
SCALABLE METHODS FOR OBTAINING RECOMBINANT VECTOR BASED ON ADENO-ASSOCIATED VIRUS (AAV) IN SYSTEM OF SERUM-FREE SUSPENSION CELL CULTURE, SUITABLE FOR CLINICAL USE 2016
  • Qu, Guang
  • Lu, Lin
  • Wright, John Fraser
RU2766583C2
AMPLIFIER AGENTS TO INCREASE CELL TRANSFECTION AND/OR rAAV VECTOR PRODUCTION 2018
  • Qu, Guang
  • Lu, Lin
  • Josue-Almqvist, Jesusa
  • Wright, John Fraser
RU2802520C2
GENETIC CONSTRUCTS AND THEIR MIXTURES FOR ANTI-HIV THERAPY 2017
  • Glazkova Dina Viktorovna
  • Bogoslovskaya Elena Vladimirovna
  • Shipulin German Aleksandrovich
  • Urusov Feliks Anatolevich
  • Pokrovskij Vadim Valentinovich
RU2666991C1
STABLE CELL LINES FOR RETROVIRUSES PRODUCTION 2016
  • Johnson, Sabine
  • Pallant, Celeste
  • Vamva, Eirini
  • Vink, Conrad
RU2752498C2
METHOD FOR TEMPORARY TRANSFECTION FOR PRODUCING RETROVIRUS 2016
  • Johnson, Sabine
  • Pallant, Celeste
  • Vamva, Eirini
  • Vink, Conrad
RU2749717C2
METHODS OF OBTAINMENT AND APPLICATION OF MULTIPOTENT CELL POPULATIONS 2008
  • Rejd Kristofer B
RU2535365C2
BUFFERS FOR STABILIZING LENTIVIRAL DRUGS 2016
  • Deb, Amitabha
  • Nebelitsky, Eugene
  • Slepushkin, Vladimir
RU2747231C2
VIRAL VECTORS CLEANING SYSTEM 2012
  • Bovolenta Kyara
  • Stornayuolo Anna
RU2607044C2

RU 2 709 678 C2

Authors

Tsyuj Guan

Rajt Dzhon Frejzer

Dates

2019-12-19Published

2014-03-17Filed