CONJUGATES AND PROSTAGLANDIN DERIVATIVES FOR TREATING GLAUCOMA AND INTRAOCULAR HYPERTENSION Russian patent published in 2020 - IPC C07C203/08 C07C201/02 C07C291/08 

Abstract RU 2712221 C2

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and specifically to a compound or a pharmaceutically acceptable salt thereof, wherein the compound is selected from the group consisting of: isopropyl-(Z)-7-((1R,2R,3R,5S)-3,5-bis(nitrooxy)-2-((R,E)-3-(nitrooxy)-4-(3-(trifluoromethyl))phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoate and (Z)-2-((((Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((R,E)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)but-1-en-1-yl)cyclopentyl)hept-5-enoyl)oxy)methoxy)-1-(pyrrolidin-1-yl)diazene-1-oxide.

EFFECT: said compounds can be used in ophthalmology.

1 cl, 2 ex

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RU 2 712 221 C2

Authors

Sharif, Najam

Scheibler, Lukas

Ellis, David

Dates

2020-01-27Published

2015-10-15Filed