METHOD OF PRODUCING AN ANTIOXIDANT AGENT IN THE FORM OF A TABLET WITH PROLONGED EFFECT Russian patent published in 2020 - IPC A61K9/22 A61K31/4425 A61K47/38 A61K47/04 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to chemical-pharmaceutical industry and medicine. Disclosed is a method of producing an antioxidant agent in the form of prolonged release, characterized in that a sifted mixture of ethyl methylhydroxypyridine succinate and hydroxypropyl methyl cellulose with viscosity of 2,700–5,040 MPa⋅with is mixed with a previously obtained moistening agent, which is an aqueous solution of hydroxypropyl methyl cellulose with viscosity of 4.8–7.2 mPa⋅s, the mixture is granulated in boiling (fluidized) layer; obtained granules are powdered with magnesium stearate and silicon with colloidal dioxide, subjected to dry granulation with subsequent pressing into tablets and film coating.

EFFECT: tablets have an improved pharmacological release profile.

4 cl, 1 tbl, 2 ex