FIELD: chemistry.
SUBSTANCE: invention relates to compositions of a double-layer tablet containing a sustained-release metformin (XR) composition or a reduced-weight metformin XR composition as a first layer, a SGLT2 inhibitor composition as a second layer and, optionally, a film coat.
EFFECT: present invention provides methods of treating diseases and disorders associated with SGLT2 activity, using the compositions of the two-layer tablet.
11 cl, 13 tbl, 15 ex
| Title |
Year |
Author |
Number |
| BI-LAYER TABLET COMPOSITION |
2010 |
- Abebe Adamassu
- Martin Kyle
- Patel Jatin M.
- Desai Divyakant
- Timmins Peter
|
RU2583920C2 |
| TWO-LAYER TABLET COMPOSITION |
2020 |
- Abebe, Admassu
- Martin, Kajl
- Patel, Dzhatin, M.
- Desai, Divyakant
- Timmins, Piter
|
RU2824129C2 |
| COMPOSITIONS OF PILL WITH IMMEDIATE RELEASE |
2010 |
- Halgren Agneta
- Swenson Ralf Magnus Werner
|
RU2558798C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING AMINO COMPOUND |
2012 |
- Narang Ajit
- Rao Venkatramana M.
- Desai Divyakant S.
|
RU2607480C2 |
| COMPOSITIONS OF METFORMIN WITH REDUCED WEIGHT |
2010 |
- Patel Dzhatin M.
- Abebe Admassu
- Timmins Piter
- Martin Kajl
|
RU2564901C2 |
| PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITOR OF HMG-REDUCTASE |
2000 |
- Krikmor Dzhozef Richard
- Uigginz Norman Al'Fred
|
RU2206324C1 |
| PHARMACEUTICAL COMBINATION, COMPOSITION, AND COMBINED FORMULATION CONTAINING A GLUCOKINASE ACTIVATOR AND AN SGLT-2 INHIBITOR, AND METHODS FOR PRODUCTION AND APPLICATION THEREOF |
2019 |
- Chen, Li
- Li, Yongguo
- Wang, Gaosen
- Gao, Huisheng
|
RU2770043C1 |
| TWO-LAYERED TABLET FOR PREVENTING CARDIOVASCULAR DISTURBANCES, DRUG AND METHOD FOR PREVENTING CARDIOVASCULAR DISTURBANCES, INCLUDING APOPLEXY AND PARALYSIS BY USING SAID TABLET |
2007 |
- Gerrero Marta
- Gul'Etta Antonio
- Orriol'S Anna
|
RU2445088C2 |
| PHARMACEUTICAL COMBINATION, COMPOSITION, AND COMBINED COMPOSITION CONTAINING GLUCOKINASE ACTIVATOR AND BIGUANIDE HYPOGLYCEMIC DRUG, AS WELL AS THEIR PREPARATION METHOD, AND THEIR USE |
2019 |
- Chen, Li
- Li, Yongguo
- Wang, Gaosen
|
RU2780377C2 |
| COMBINED COMPOSITION CONTAINING METFORMIN OF SUSTAINED RELEASE AND INHIBITOR HMG-CoA-REDUCTASE OF IMMEDIATE RELEASE |
2014 |
- Kang Kwi Man
- Park Young Joon
- Park Jun Hong
- Lee Ji Eun
- Yoon Seok Kee
- Kim Yu Jeong
- Oh Tack Oon
- Cho Tae Keun
|
RU2651460C2 |
