COMBINATION THERAPY FOR TREATING CANCER WITH POXVIRUS EXPRESSING TUMOUR ANTIGEN AND ANTAGONIST AND/OR AGONIST OF IMMUNE CHECKPOINT INHIBITOR Russian patent published in 2020 - IPC A61K39/275 A61K39/395 A61P35/00

Abstract RU 2714142 C2

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Disclosed is a therapeutic agent for treating a human having cancer containing recombinant orthopoxvirus MVA-BN and an antagonist of anti-PD-1, which is an antibody. Disclosed is a method of treating a human having cancer, comprising administering to a patient a recombinant orthopoxvirus MVA-BN and said antagonist.

EFFECT: proposed group of inventions provides a synergetic effect associated with recombinant orthopoxvirus and antagonist anti-PD-1.

22 cl, 23 dwg, 24 ex

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RU 2 714 142 C2

Authors

Rauntri, Rajan

Foj, Syuzan

Mendl, Stefani

Delker, Alen

Dates

2020-02-12—Published

2014-10-31—Filed