FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology, specifically to immunology, and can be used to produce foot-and-mouth disease virus (FMDV) vaccines. Composition containing the FMDV antigen - FMDV-dihydrolipoyl-acetyltransferase (E2) fusion protein - is obtained. Fusion protein FMDV-E2 is able to form particles similar to natural virions FMDV or VLP FMDV.
EFFECT: invention provides the effective foot-mouth disease vaccine, susceptible to FMDV vaccination of animal, cattle, goat or pig.
19 cl, 11 dwg, 4 tbl, 2 ex
| Title | Year | Author | Number |
|---|---|---|---|
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|
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| ALPHAVIRUS REPLICON PARTICLE | 2018 |
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| VACCINE COMPOSITION AGAINST INFECTION CAUSED BY STREPTOCOCCUS SUIS | 2015 |
|
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| DISPLAY OF AN INTEGRAL MEMBRANE PROTEIN ON EXTRACELLULAR ENVELOPED POXVIRUS VIRIONS | 2017 |
|
RU2759846C2 |
| IMMUNOGENIC FUSED PROTEIN | 2016 |
|
RU2757426C2 |
| GLYCOSYLATED FUSED PROTEINS VWF WITH IMPROVED PHARMACOKINETICS | 2017 |
|
RU2782212C2 |
