FIELD: medicine; pharmaceuticals.
SUBSTANCE: invention relates to novel functionalized derivatives of morpholinylanthracycline, which have cytotoxic activity and are applicable for treating diseases such as cancer, cell proliferative diseases and viral infections. Also disclosed are pharmaceutical compositions containing said compounds, and methods of treating diseases using such compounds or pharmaceutical compositions containing them. Invention also relates to the use of these derivatives for producing conjugates.
EFFECT: functionalised derivatives of morpholinylanthracycline are proposed.
6 cl, 6 dwg, 1 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW MORPHOLINYL ANTHRACYCLINE DERIVATIVES | 2014 |
|
RU2666356C2 |
| COMPOUNDS AND METHODS FOR TREATMENT OF PARASITIC DISEASES | 2018 |
|
RU2793122C2 |
| NEW ALKYLATING AGENTS | 2013 |
|
RU2632206C2 |
| COMPOSITIONS SUITABLE FOR TREATING DISORDERS ASSOCIATED WITH KIT | 2014 |
|
RU2706235C2 |
| POLYCYCLIC COMPOUND ACTING AS KINASE INHIBITOR | 2021 |
|
RU2826488C1 |
| SECONDARY MANNOSIS FOR BACTERIAL INFECTIONS TREATMENT | 2013 |
|
RU2667060C2 |
| MANNOSE DERIVATIVES FOR TREATING BACTERIAL INFECTIONS | 2014 |
|
RU2678327C2 |
| COMPOSITIONS AND METHODS OF TREATMENT OF DISEASES OF CENTRAL NERVOUS SYSTEM | 2018 |
|
RU2810331C2 |
| 7-DEOXYDERIVATIVES OF TAXOL, DERIVATIVES OF BACCATINE, 10-PENTAFLUOROPHENYLBACCATINE, 7-[(METHYLTHIO)CARBONOTHIOYLHYD- -ROXY]-13-TRIETHYLSILYLHYDROXYBACCATINE, PHARMACEUTICAL COMPOSITION | 1993 |
|
RU2122545C1 |
| COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS | 2015 |
|
RU2733756C2 |
