FIELD: biotechnology; medicine.
SUBSTANCE: present invention relates to biotechnology and can be used in medicine. Invention discloses new non-peptide protein kinase inhibitors. Compounds according to the present invention are characterized by general formula (I) and represent a class of organic compounds containing tricyclic heteroaryl groups.
EFFECT: invention can be used in treating diseases in which there is an increased activity of CDK and/or TRK kinases.
18 cl, 27 ex, 2 tbl
Title |
Year |
Author |
Number |
HETEROCYCLIC AMIDE COMPOUND, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, METHOD FOR PREPARATION AND USE THEREOF |
2020 |
- Duan, Wenhu
- Geng, Meiyu
- Zhang, Huibin
- Xie, Zuoquan
- Zhou, Jinpei
- Yang, Yifei
- Wang, Xiyuan
- Yang, Xiaojun
- Zhang, Yan
- Hu, Zhaoxue
- Ding, Jian
|
RU2823875C1 |
TETRAHYDROISOQUINOLINE COMPOUND AS A POTASSIUM CHANNELS MODULATOR, ITS PREPARATION AND APPLICATION |
2021 |
- Liang, Bo
- Liu, Gang
- Chen, Huanming
|
RU2800873C1 |
NEURAMINIC ACID DERIVATIVES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS, OR THEIR ESTERS AND A PHARMACEUTICAL COMPOSITION EXHIBITING SIALIDASE-INHIBITING ACTIVITY |
1997 |
- Takesi Khonda
- Josijuki Kobajasi
- Takesi Masuda
- Makoto Jamasita
- Masami Arai
|
RU2124509C1 |
7-DEOXYDERIVATIVES OF TAXOL, DERIVATIVES OF BACCATINE, 10-PENTAFLUOROPHENYLBACCATINE, 7-[(METHYLTHIO)CARBONOTHIOYLHYD- -ROXY]-13-TRIETHYLSILYLHYDROXYBACCATINE, PHARMACEUTICAL COMPOSITION |
1993 |
- Vittorio Farina
- Shu-Kh'Ju Chen
- Dehvid R.Lehngli
- Mark D.Uittman
- Dzhojdip Kehnt
- Dolatraj Vajs
|
RU2122545C1 |
1,3-OXATHIOLANE, GEOMETRICAL AND OPTICAL ISOMERS THEREOF, MIXTURES OF SAID ISOMERS, METHODS OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION HAVING ANTIVIRAL ACTIVITY |
1990 |
- Bernar Bello[Ca]
- P'Erett Bello[Ca]
- Nge Nguen-Ba[Ca]
|
RU2092485C1 |
THIENOPYRIMIDINE COMPOUNDS, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION |
1996 |
- Suiti Furuja
- Nobuo Tokh
- Koiti Kato
- Sudzi Khinuma
|
RU2158739C2 |
HYDROGENATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS, DERIVATIVES OF PYPERIDINE, PHARMACEUTICAL COMPOSITION AND METHOD FOR SUPPRESSING ACTIVITY OF P COMPOUND IN ORGANISM |
1991 |
- Manodzh S.Desaj[In]
- Terri Dzh.Rosen[Us]
|
RU2105758C1 |
PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS AND THERAPEUTIC APPLICATIONS THEREOF |
2015 |
- Tao, Chunlin
- Wang, Qinwei
- Nallan, Laxman
- Ho, David
- Polat, Tulay
- Arp, Forrest
- Weingarten, Paul
|
RU2701188C2 |
INHIBITORS OF HIV-PROTEASE |
1994 |
- Dzhoel R.Khaff
- Dzhozef P.Vakka
- Brjus D.Dorsi
|
RU2137768C1 |
BENZIMIDAZOLE DERIVATIVES AS ROR-GAMMA MODULATORS |
2017 |
- Klermon Devid A.
- Dillard Lourens Uejn
- Fan I
- Lotesta Stiven D.
- Singkh Suresh B.
- Tajs Kolin M.
- Chzhao Vei
- Chzhuan Linkhan
|
RU2760366C2 |