COMPOSITIONS AND METHODS OF TREATING FUNGAL AND BACTERIAL PATHOGENS Russian patent published in 2020 - IPC C07K14/40 A61K39/00 C07K16/14 C07K19/00 A61K39/395 C12N15/31 C12N15/63 C12N5/10 A61P31/10 G01N33/53 

Abstract RU 2717306 C2

FIELD: biotechnology.

SUBSTANCE: present invention relates to biotechnology. Disclosed is an isolated polypeptide which is a Hyr1 protein fragment Candida albicans, for mammal vaccination. Invention also discloses: a nucleic acid molecule encoding said polypeptide, an expression vector, a cell, a polypeptide production method, an antigen composition and a method for preparing it, as well as a method for inducing an immune response.

EFFECT: said polypeptide has immunogenic properties not only in relation to yeast Candida albicans, but also against gram-negative bacteria Acinetobacter baumannii.

23 cl

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RU 2 717 306 C2

Authors

Ibrahim Ashraf S.

Yeaman Michael R.

Filler Scott G.

Edwards John E. Jr.

Hennessey John P. Jr.

Dates

2020-03-19Published

2014-03-14Filed