FIELD: biotechnology.
SUBSTANCE: provided vaccine compositions comprise a pharmaceutically acceptable carrier and a first polypeptide having at least 95% identity with the amino acid sequence of SEQ ID NO: 265, 266 or 268, and a second polypeptide having at least 90% identity with the amino acid sequence of SEQ ID NO 9, 10, 20, 21, 6, 7, 18 or 19.
EFFECT: invention can be used for the prevention or treatment of diseases caused by S pneumoniae.
58 cl, 19 dwg, 4 tbl, 18 ex
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