FIELD: chemistry.
SUBSTANCE: group of inventions relates to dental paste and related methods and kit. Disclosed is a dental paste containing: (i) a compound of formula I:
wherein: R1 is C1-C2 alkyl group, and R2 is C(O)R3, where R3 is C7-C9 alkyl group and n is integer 4; (ii) a compound of formula II or a pharmaceutically acceptable salt thereof:
wherein: R4 represents a hydrogen atom or C1-C12 alkyl group and m denotes integer 4; and (iii) dental abrasive. Invention also discloses a method for treating a surface in an oral cavity of a subject and a method of inhibiting biofilm formation on a surface in an oral cavity of a subject, each of which involves the stage of application of said dental paste on the surface in the oral cavity of the individual. In addition, a kit for treating a surface in the oral cavity of a subject, comprising said dental paste and an applicator, is provided.
EFFECT: use of said dental paste provides higher effectiveness of inhibiting the formation of biofilm on the surface of the oral cavity compared to dental pastes containing only one of compounds of formula I or formula II.
17 cl, 6 tbl
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|
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