FIELD: medicine; pharmaceuticals.
SUBSTANCE: group of inventions refers to pharmaceutical industry, namely to a biomedical cell product (BMCP) for regeneration of nerve tissue, a method for preparing and using it. Biomedical cell product (BMCP) for regeneration of nerve tissue contains autologous or immunocompatible allogenic cleaned mobilized mononuclear cells (MNC) of human peripheral blood leukonocentrate (LC) (component A) containing hematopoietic progenitor cells (HPC) in amount of 1–2 % of total MNC number and mesenchymal stromal progenitor cells (MSPC) in amount of 1–1.5 % of the total number of MNC cells, a line of autologous or immunosupersistent allogenic mesenchymal stromal stem cells (MSSC) pre-processed in a biologically stable medium inducing their neural differentiation (component B), and an adjuvant in the form of a sterile transfusion medium at the following cell concentrations per 1 ml of the adjuvant: component A (MNC) - 1.75 × 105 - 4 × 106 cells; component B (MSSC) - 3 × 105 - 1.5 × 106 cells.
EFFECT: invention discloses a biomedical cell product for treating nervous diseases and mental disorders, a method for preparing it and use thereof.
10 cl, 7 tbl, 3 ex
Title | Year | Author | Number |
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BIOMEDICAL CELL PRODUCT, METHOD FOR ITS PRODUCTION AND APPLICATION | 2018 |
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ANTITUMOR TARGET CELL PRODUCT, METHOD FOR ITS PRODUCTION AND ITS APPLICATION | 2018 |
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METHOD FOR OBTAINING BIOMEDICAL CELL PRODUCT FOR TREATMENT OF ONCOLOGICAL, NEURODEGENERATIVE AND AUTOIMMUNE DISEASES | 2019 |
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BIOMEDICAL CELL PREPARATION | 2017 |
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BIOMEDICAL CELL PRODUCT FOR THE TREATMENT OF ONCOLOGICAL, NEURODEGENERATIVE, AUTOIMMUNE DISEASES AND INJURIES OF THE BRAIN AND SPINAL CORD | 2021 |
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PERSONALIZED METHOD OF BONE MARROW RESTITUTION FOR CONTROLLING PROGRESSION AND RECURRENCES OF VARIOUS CIVILIZATION DISEASES, PREVENTING AGING AND SUDDEN DEATH | 2023 |
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RU2817892C1 |
METHOD FOR REMOTE ELECTROMAGNETIC MULTIWAVE RADIO NEUROENGINEERING OF HUMAN BRAIN | 2015 |
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IMPLANTED NEUROENDOPROSTHETIC SYSTEM, METHOD OF OBTAINING IT AND METHOD OF CARRYING OUT RECONSTRUCTIVE NEUROSURGICAL OPERATION | 2008 |
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RU2394593C2 |
STEM CELL PREPARATION WITH REPROGRAMMED CELL SIGNALLING, METHOD FOR MAKING THIS PREPARATION AND APPLICATION THEREOF | 2008 |
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RU2428475C2 |
ANTICANCER INDIVIDUAL PROTEOME-BASED TARGET CELL PREPARATION, METHOD FOR PRODUCING AND USING THIS PREPARATION FOR THERAPY OF CANCER AND OTHER MALIGNANT NEW GROWTHS | 2012 |
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Authors
Dates
2020-04-23—Published
2018-12-28—Filed