BIOMEDICAL CELL PRODUCT FOR TREATING NERVOUS DISEASES AND MENTAL DISORDERS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF Russian patent published in 2020 - IPC A61K35/14 A61P25/00 

Abstract RU 2720002 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions refers to pharmaceutical industry, namely to a biomedical cell product (BMCP) for regeneration of nerve tissue, a method for preparing and using it. Biomedical cell product (BMCP) for regeneration of nerve tissue contains autologous or immunocompatible allogenic cleaned mobilized mononuclear cells (MNC) of human peripheral blood leukonocentrate (LC) (component A) containing hematopoietic progenitor cells (HPC) in amount of 1–2 % of total MNC number and mesenchymal stromal progenitor cells (MSPC) in amount of 1–1.5 % of the total number of MNC cells, a line of autologous or immunosupersistent allogenic mesenchymal stromal stem cells (MSSC) pre-processed in a biologically stable medium inducing their neural differentiation (component B), and an adjuvant in the form of a sterile transfusion medium at the following cell concentrations per 1 ml of the adjuvant: component A (MNC) - 1.75 × 105 - 4 × 106 cells; component B (MSSC) - 3 × 105 - 1.5 × 106 cells.

EFFECT: invention discloses a biomedical cell product for treating nervous diseases and mental disorders, a method for preparing it and use thereof.

10 cl, 7 tbl, 3 ex

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RU 2 720 002 C1

Authors

Bryukhovetskij Andrej Stepanovich

Abashin Igor Mikhajlovich

Dates

2020-04-23Published

2018-12-28Filed