STEM CELL PREPARATION WITH REPROGRAMMED CELL SIGNALLING, METHOD FOR MAKING THIS PREPARATION AND APPLICATION THEREOF Russian patent published in 2011 - IPC C12N5/95 C12N5/10 A61K9/51 A61P35/00 

FIELD: medicine.

SUBSTANCE: substance of the invention involves a stem cell (SC) preparation with reprogrammed cell signalling containing a base SC preparation in a membrane and/or a nucleus and/or a cytoplasm of which there is implanted a protein or pharmaceutical preparation capable to regulate signalling pathways of the SC and nidus cells in a mammal's body, pre-encapsulated in a nanocontainer with dimensions of 100 nm, produced of a biodegradable material, intact for organelles and compartments of the SC of the base preparation. This material has the preset biodegradation time in a mammal's body to provide the programmed protein or pharmaceutical preparation recovery in an intra- or intercellular space and to implement thereby reprogramming of signalling transduction of the SC key genes in a required therapeutic pattern of physiological cell cycle events directly in a pathological body region or tissue.

EFFECT: provided target addition of the signalling substances strictly in the involved body region.

14 cl, 6 ex, 3 dwg