FIELD: medicine; oncology; neurology.
SUBSTANCE: biomedical cell product for the treatment of oncological or neurological diseases comprises a line of autologous or immuno-compatible allogenic mesenchymal stromal stem cells (MSSC) with markers CD10+, CD13+, CD44+, CD90+ (Thy-1), CD105+, CD34−, CD45− and CD117− and mesenchymal stromal progenitor cells (MSPC) with markers CD10+, CD13+, CD44−, CD90+ (Thy-1), CD105+, CD34+, CD45+ and CD117+, recovered from native bone marrow or adipose tissue and cultured in vitro in a medium promoting mesenchymal differentiation (component A), non-manipulated autologous or allogenic mobilized mononuclear cells (MNC) recovered from peripheral blood leuconcentrate (PB LC), purified from blood plasma, erythrocytes and granulocytes (component B), and an auxiliary substance in the form of a sterile transfusion medium (component B), with the following ratio of components (vol % of the total amount of the BMLI): component A—1–19.5; component B—79.5–90; component B is rest. Group of inventions also relates to a method for obtaining ex tempore of said biomedical cell product and use thereof for treating oncological and neurological diseases.
EFFECT: group of inventions can be used in treating malignant neoplasms and neurological diseases.
10 cl, 9 tbl, 1 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| BIOMEDICAL CELL PRODUCT FOR TREATING NERVOUS DISEASES AND MENTAL DISORDERS, METHOD FOR PRODUCTION THEREOF AND USE THEREOF | 2018 |
|
RU2720002C1 |
| ANTITUMOR TARGET CELL PRODUCT, METHOD FOR ITS PRODUCTION AND ITS APPLICATION | 2018 |
|
RU2757812C2 |
| METHOD FOR OBTAINING BIOMEDICAL CELL PRODUCT FOR TREATMENT OF ONCOLOGICAL, NEURODEGENERATIVE AND AUTOIMMUNE DISEASES | 2019 |
|
RU2774350C2 |
| BIOMEDICAL CELL PREPARATION | 2017 |
|
RU2647429C1 |
| PERSONALIZED METHOD OF BONE MARROW RESTITUTION FOR CONTROLLING PROGRESSION AND RECURRENCES OF VARIOUS CIVILIZATION DISEASES, PREVENTING AGING AND SUDDEN DEATH | 2023 |
|
RU2817892C1 |
| METHOD OF EARLY MOLECULAR-BIOLOGICAL DIAGNOSIS OF MALIGNANT GROWTHS AND AMYOTROPHIC LATERAL SCLEROSIS | 2018 |
|
RU2706714C1 |
| ANTICANCER INDIVIDUAL PROTEOME-BASED TARGET CELL PREPARATION, METHOD FOR PRODUCING AND USING THIS PREPARATION FOR THERAPY OF CANCER AND OTHER MALIGNANT NEW GROWTHS | 2012 |
|
RU2535972C2 |
| BIOMEDICAL CELL PRODUCT FOR THE TREATMENT OF ONCOLOGICAL, NEURODEGENERATIVE, AUTOIMMUNE DISEASES AND INJURIES OF THE BRAIN AND SPINAL CORD | 2021 |
|
RU2798554C2 |
| METHOD FOR REMOTE ELECTROMAGNETIC MULTIWAVE RADIO NEUROENGINEERING OF HUMAN BRAIN | 2015 |
|
RU2621547C2 |
| STEM CELL PREPARATION WITH REPROGRAMMED CELL SIGNALLING, METHOD FOR MAKING THIS PREPARATION AND APPLICATION THEREOF | 2008 |
|
RU2428475C2 |
