DEVICE FOR MEASURING SPECTRUM OF IMPEDANCE OF BIOLOGICAL STRUCTURES Russian patent published in 2020 - IPC G01N27/02 G01N33/49 

FIELD: measuring equipment.

SUBSTANCE: invention relates to the field of measurement equipment and can be used for measurement of impedance spectrum of biological tissues and organs of mammals, in particular, samples of in vitro models of barrier tissues in biological experiments, and also enables to measure impedance of various solutions in order to determine their physical properties (concentration, conductivity, and so forth). Device for measuring the spectrum of impedance of biological structures includes a housing consisting of three parts: a base with a control board, a cover with a display board and a middle part, which includes a frame placed between the base and the cover. On the outer side of the cover there are two displays for displaying measurement results. Control board comprises control microcontroller, power supply unit, measuring input cascade and output stage of sinusoidal current with constant amplitude, memory unit, connector for switching with indication board, at least four connectors for connection to containers with biological structures through a switching board, a signal connector for switching between a control board and a switching board, a power supply connector, connector for connection to peripheral devices and an encoder, which provides selection of measurement frequency and switching between frequency bands. Display board comprises a mating connector for switching with a control board, connectors for connecting displays and control buttons, comprising a start button of the measurement process, menu navigation buttons, switching buttons between graphs, displaying measured parameters, and rotary switch, providing selection of stored measurement file for viewing. Cover is provided with through holes arranged in accordance with the arrangement of buttons, rotary switch and encoder, and the frame is equipped with protective inserts fixed in the attachment zone of control board connectors, equipped with holes corresponding to control card slots. Indicating light-emitting diodes are mounted in the housing, which are fixed with possibility of radiation onto the frame. Between the base and the control board there is an insulating gasket. Frame is made of light-scattering material for output of light indication from light-emitting diodes.

EFFECT: technical result is fast and easy assembly and operation of the device for measuring the impedance spectrum of biological structures cultivated on membrane inserts placed in a multi-well plate or microfluidic chip.

5 cl, 17 dwg