THERAPEUTIC AGENT FOR LIVER DISEASES Russian patent published in 2020 - IPC A61K31/4439 A61P1/16 

Abstract RU 2723686 C1

FIELD: medicine; pharmaceuticals.

SUBSTANCE: disclosed is a pharmaceutical composition for preventing or treating fatty liver disease, comprising as an active ingredient a pyrazole-based compound or a pharmaceutically acceptable salt thereof.

EFFECT: compound 3-phenyl-4-alkyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol and its pharmaceutically acceptable salt are able to effectively inhibit fatty hepatosis, hepatic inflammation and hepatic fibrosis and are useful for preventing or treating NAFLD, in particular nonalcoholic steatohepatitis.

10 cl, 3 ex, 6 dwg

Similar patents RU2723686C1

Title Year Author Number
AGENT FOR PULMONARY FIBROSIS CONTAINING PYRAZOLE DERIVATIVE 2021
  • Moon, Sung Hwan
  • Lee, Soo Jin
  • Yu, Hyunkyung
  • Goh, Yoo-Kyung
RU2817989C1
AGENT FOR TREATING ACUTE RENAL INJURY CAUSED BY CONTRAST AGENT 2021
  • Lee, Soo Jin
  • Moon, Sung Hwan
RU2817980C1
COMPOSITION FOR PREVENTING OR TREATING FATTY LIVER DISEASES 2015
  • Kim Soon Kha
  • Kim Khioung Dzin
  • Park Kheui Sul
  • Akhn Seo Khiun
  • Shong Min Kho
  • Chung Khio Kiun
RU2664696C2
NEW CRYSTAL SOLID COMPOUND OF 3-PHENYL-4-PROPYL-1-(PYRIDINE-2-YL)-1H-PYRAZOL-5-OL HYDROCHLORIDE 2018
  • Moon, Sung Hwan
  • Lee, Soo Jin
  • Lee, Sung Chan
RU2754255C2
NOVEL PHARMACEUTICAL USE OF THIENO[3,2-D]PYRIMIDIN-4-ONE COMPOUNDS 2019
  • Liu, Hong
  • Li, Jia
  • Wang, Jiang
  • Zang, Yi
  • Li, Jian
  • Li, Jingya
  • Sun, Dandan
  • Jiang, Hualiang
  • Chen, Kaixian
RU2768828C1
NOVEL PYRAZOLE DERIVATIVES 2022
  • Lee Soo Jin
  • Moon Sung Hwan
  • Ban Sooho
  • Lee Eunsil
  • Shin Eun Jung
  • Goh Yoo-Kyung
RU2816835C1
TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE 2019
  • Li, Chian Dzh.
  • Derdak, Zoltan
  • Lyu, Tszifen
RU2815647C2
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NON-ALCOHOLIC STEATHOEPATITIS 2021
  • Kim, Mi-Kyung
  • Park, Hansu
  • Lee, Seung Ho
RU2803733C1
USING LACTITOL AND AN ORAL DOSAGE FORM FOR TREATING AND PREVENTING NON-ALCOHOLIC FATTY LIVER DISEASE 2018
  • Nesteruk Vladimir Viktorovich
  • Syrov Kirill Konstantinovich
RU2692243C1
PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NON-ALCOHOLIC FATTY LIVER INFILTRATION, CONTAINING GPR119 LIGAND AS ACTIVE INGREDIENT 2019
  • Kim, Mi-Kyung
  • Lee, Bo Ram
  • Park, Hansu
  • Lee, Seung Ho
  • Chae, Yu Na
RU2768943C1

RU 2 723 686 C1

Authors

Moon, Sung Hwan

Lee, Soo Jin

Lee, Sung Chan

Bae, Yun Soo

Dates

2020-06-17Published

2018-09-14Filed