NOVEL DERIVATIVES OF POLYOLS, USE THEREOF, A PHARMACEUTICAL COMPOSITION BASED THEREON Russian patent published in 2020 - IPC C07D233/64 A61K31/417 A61P31/12 A61P31/16 

Abstract RU 2726119 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a novel compound of general formula (I) and a pharmaceutically acceptable salt thereof of general formula (I). Compounds can be used for treating and / or preventing respiratory diseases selected from a group consisting of rhinitis, sinusitis, rhinosinusitis, pharyngitis, nasopharyngitis, tonsillitis, vocal folds and larynx diseases, vasomotor and allergic rhinitis, bronchitis, bronchiolitis, pneumonia, bronchial asthma, chronic obstructive pulmonary disease, cystic fibrosis. In particular, the compounds can be used for treating and / or preventing viral infection mediated diseases, such as rhinovirus, respiratory syncytial virus, parainfluenza virus, influenza virus, adenovirus, metapneumovirus, coronavirus, Coxsackie virus, enterovirus, rotavirus, herpes virus. In general formula (I)

(I)

at least one of R is .

EFFECT: compounds have antiviral and anti-inflammatory activity.

8 cl, 4 dwg, 5 tbl, 2 ex

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RU 2 726 119 C1

Authors

Golubeva Natalya Aleksandrovna

Dates

2020-07-09Published

2019-11-22Filed