FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry, specifically to use of 4H-3,1-benzoxazin-4-one derivative of general formula 1
,
where R1, R2, R3, R4, R5, R6, R7, R8, R9 are optionally identical and are hydrogen, C1-C6 alkyl, halogen, C1-C6 alkoxy, oxycarbonyl of formula -OC(O)R, where R is C 1 -C 6 alkyl, as an inhibitor of hepatitis B virus for preparing a drug for treating hepatitis B. Also disclosed is a pharmaceutical composition comprising a compound of general formula 1.
EFFECT: technical result: use of 4H-3,1-benzoxazin-4-one derivative as an inhibitor of hepatitis B virus is disclosed.
7 cl, 1 tbl, 26 ex
| Title | Year | Author | Number |
|---|---|---|---|
| HEPATITIS B VIRUS INHIBITOR (HBV) | 2019 |
|
RU2736975C1 |
| HEPATITIS B VIRUS (HBV) INHIBITOR | 2019 |
|
RU2746423C2 |
| HEPATITIS B VIRUS (HBV) INHIBITOR, WHICH IS A DERIVATIVE OF N-{3-[6-(DIALKYLAMINO)PYRIDAZINE-3-YL]PHENYL}ARYL SULPHONAMIDE DERIVATIVES AND DERIVATIVES OF N-{4-[6-(DIALKYLAMINO)PYRIDAZINE-3-YL]PHENYL}ARYL SULPHONAMIDE | 2019 |
|
RU2738848C1 |
| MACROHETEROCYCLIC NUCLEOSIDE DERIVATIVES AND ANALOGUES THEREOF, PRODUCTION AND USE | 2017 |
|
RU2731385C1 |
| PAN-GENOMIC INHIBITORS OF THE HEPATITIS C VIRUS PROTEIN NS5A, PHARMACEUTICAL COMPOSITIONS, INTERMEDIATES FOR THE SYNTHESIS OF INHIBITORS, AND METHODS FOR THEIR PREPARATION AND USE | 2016 |
|
RU2669919C1 |
| NUCLEOTIDES INCLUDING N-[(S)-1-CYCLOBUTOXYCARBONYL]PHOSPHORAMIDATE FRAGMENT, THEIR ANALOGS AND THEIR APPLICATION | 2017 |
|
RU2659388C1 |
| SUBSTITUTED AZOLES, ANTIVIRAL ACTIVE COMPONENT, PHARMACEUTICAL COMPOSITION, SYNTHESIS AND APPLICATION METHOD | 2010 |
|
RU2452735C1 |
| ALKYL [2-(2-{5-[4-(4-{2-[1-(2-METHOXYCARBONYLAMINO-ACETYL)-PYRROLIDIN-2-YL]-3H-IMIDAZOL-4-YL}-PHENYL)-BUTA-1,3-DIINYL]-1H-IMIDAZOL-2-YL}-PYRROLIDIN-1-YL)-2-OXO-ETHYL]-CARBAMATE, PHARMACEUTICAL COMPOSITION, MEDICATION, METHOD OF TREATING VIRAL DISEASES | 2013 |
|
RU2518369C1 |
| SUBSTITUTED INDOLES, ANTIVIRAL ACTIVE COMPONENT, SYNTHESIS AND APPLICATION METHOD | 2010 |
|
RU2436786C1 |
| PARTIAL AGONIST OF DOPAMIN D2/D3 RECEPTORS - 4-{2-[4-(2,3-DICHLOROPHENIL)-PIPERAZIN-1-YL]-ETHYL}-PYPERIDIN-1-CARBONIC ACID METHILAMIDE, METHODS (OPTIONS) OF ITS OBTAINMENT AND APPLICATION | 2018 |
|
RU2677268C1 |
