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2 738 848

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IPC

C07D403/04(2006-01-01)

C07D401/04(2006-01-01)

A61K31/50(2006-01-01)

A61K31/501(2006-01-01)

A61P31/12(2006-01-01)

A61P1/16(2006-01-01)

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Application

2019134150, 2019-10-24

(24)

Start date

2019-10-24

(22)

Actual filing date

2019-10-24

(45)

Published

2020-12-17

(72)

Inventor

Ivashchenko Andrej AleksandrovichIvashchenko Aleksandr VasilevichSavchuk Nikolaj FilippovichMitkin Oleg DmitrievichKravchenko Dmitrij VladimirovichKovalenko Sergej NikolaevichBunyatyan Natalya Dmitrievna

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu Institut Khimrar" Khimrar")

HEPATITIS B VIRUS (HBV) INHIBITOR, WHICH IS A DERIVATIVE OF N-{3-[6-(DIALKYLAMINO)PYRIDAZINE-3-YL]PHENYL}ARYL SULPHONAMIDE DERIVATIVES AND DERIVATIVES OF N-{4-[6-(DIALKYLAMINO)PYRIDAZINE-3-YL]PHENYL}ARYL SULPHONAMIDE Russian patent published in 2020 - IPC C07D403/04 C07D401/04 A61K31/50 A61K31/501 A61P31/12 A61P1/16

Abstract RU 2738848 C1

FIELD: pharmaceuticals.

SUBSTANCE: invention relates to use of compounds, which are N-{3-[6-(pyrrolidin-1-yl)pyridazin-3-yl]phenyl}-2-(trifluoromethyl)benzenesulphonamide, N-{3-[6-(piperidin-1-yl)pyridazine-3-yl]phenyl}-2,4,6-trimethylbenzene sulfonamide, N-{3-[6-(piperidin-1-yl)pyridazin-3-yl]phenyl}-4-(trifluoromethyl)benzenesulphonamide, etc., specified in the patent claim, for inhibiting hepatitis B virus (HBV) infection.

EFFECT: disclosed is a hepatitis B virus (HBV) inhibitor, which is a derivative of N-{3-[6-(dialkylamino)pyridazin-3-yl]phenyl}aryl sulphonamide and derivatives of N-{4-[6-(dialkylamino)pyridazin-3-yl]phenyl}aryl sulphonamide.

1 cl, 1 tbl, 25 ex

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RU 2 738 848 C1

Authors

Ivashchenko Andrej Aleksandrovich

Ivashchenko Aleksandr Vasilevich

Savchuk Nikolaj Filippovich

Mitkin Oleg Dmitrievich

Kravchenko Dmitrij Vladimirovich

Kovalenko Sergej Nikolaevich

Bunyatyan Natalya Dmitrievna

Dates

2020-12-17—Published

2019-10-24—Filed