FIELD: pharmaceuticals.
SUBSTANCE: invention relates to derivatives of 4-(1,3-thiazol-2-yl)thiophene-2-sulphonamide of general formula 1, having properties of hepatitis B virus (HBV) inhibitor, a method for production thereof, pharmaceutical composition based thereon and use thereof for preparing a medicament for treating hepatitis B. In general formula 1, R1 is C1-C4 alkyl, R2 is hydrogen, C1-C4 alkyl, or R3 is hydrogen, and R4 is C5 alkyl, 4-isopropylbenzyl, phenyl substituted with 1–2 substitutes selected from F, Cl, Br, methyl, isopropyl, methoxy and COOCH3.
EFFECT: hepatitis B virus (HBV) inhibitor.
12 cl, 1 tbl, 29 ex
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