INDOLIN-2-ONE DERIVATIVES Russian patent published in 2020 - IPC A61K31/44 A61K31/506 A61K31/519 A61K31/551 A61K31/5513 A61K45/00 A61P11/06 A61P19/02 A61P21/00 A61P25/00 A61P25/04 A61P25/08 A61P25/14 A61P25/16 A61P25/18 A61P25/20 A61P25/22 A61P25/24 A61P25/28 A61P25/30 A61P25/32 A61P25/36 A61P27/02 A61P31/10 A61P31/12 A61P37/02 A61P9/10 C07D401/14 C07D403/14 C07D471/04 

Abstract RU 2727179 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: present invention relates to indolin-2-one derivatives.

EFFECT: said compounds can be used for treating CNS diseases associated with positive (psychosis) and negative symptoms of schizophrenia, abuse of drugs, alcohol and drug addiction, obsessive-compulsive disorders, cognitive disorders, bipolar disorders, mood disorders, deep depression, therapeutically resistant depression, anxiety disorders, Alzheimer's disease, autism, Parkinson's disease, chronic pain, borderline personality disorder, neurodegenerative diseases, sleep disorders, chronic fatigue syndrome, stiffness, inflammatory diseases, asthma, Huntington's disease, ADHD, amyotrophic lateral sclerosis, arthritis, autoimmune diseases, viral and fungal infections, cardiovascular diseases, ophthalmic and inflammatory retinal diseases and disturbed equilibrium, epilepsy and CNS development disorders accompanying epilepsy.

25 cl, 3 tbl, 46 ex

Similar patents RU2727179C2

Title Year Author Number
INDOLIN-2-ONE OR PYRROLO-PYRIDIN/PYRIMIDIN-2-ONE DERIVATIVES 2014
  • Brunner Daniela
  • Khilpert Khans
  • Koltsevski Sabina
  • Limberg Anya
  • Melberg Dzhessika
  • Prinssen Erik
  • Rimer Klaus
  • Shankar Bavani G.
  • Shtoll Teodor
RU2666532C2
INDOLIN-2-ONE AND 1,3-DIHYDRO-PYRROLO[3,2-C]PYRIDIN-2-ONE DERIVATIVES 2015
  • Khilpert Khans
  • Koltsevski Sabina
  • Limberg Anya
  • Shtoll Teodor
RU2697512C2
OXYINDOLE DERIVATIVES POSSESSING AGONIST ACTIVITY ON MOTILIN RECEPTOR 2010
  • Sudo Masaki
  • Ivata Jasukhiro
  • Arano Josimasa
  • Dzinno Madoka
  • Okhmi Masasi
  • Noguti Khirokhide
RU2533116C2
2-PHENYLIMIDAZO[1,2-A]PYRIMIDINES AS IMAGING AGENTS 2014
  • Gobbi Luka
  • Knust Khenner
  • Kerner Mattias
  • Muri Diter
RU2665580C2
PYRROL[2,3-B]PYRAZINES AS SYK INHIBITORS 2013
  • Germann Jokhannes Kornelius
  • Kennedi-Smit Dzhoshua
  • Lukas Metyu S.
  • Pedilla Fernando
  • Shoenfeld Rajan Krejg
  • Vovkulich Piter Majkl
RU2656853C2
BENZOTHIAZOLE COMPOUNDS AND METHODS FOR THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS 2018
  • Li, Dzhinkhva
  • Cho, Suen
  • Pak, A En
  • Li, Gvibin
  • Kim, Dzhe Yn
  • Kim, Misun
  • Dzhun, Kesyn
  • Lim, Syn Muk
  • Lim, Kensyn
  • Li, Minvu
  • Yan, Khiken
  • Kim, Khenam
  • Kim, Khendzhun
  • Li, Vantszyun
  • Fan, Minchzhu
RU2778370C2
ARYLETHINYL DERIVATIVES 2011
  • Grin Ljuk
  • Guba Vol'Fgang
  • Eshke Georg
  • Zholidon Siniz
  • Lindemann Lotar
  • Richchi Antonio
  • Rjukher Daniehl'
  • Shtadler Khajnts
  • Viejra Ehrik
RU2573560C2
DERIVATIVES OF N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDES AND THEREOF APPLICATION AS PDE10A INHIBITORS 2011
  • Al'Vares Sanches Ruben
  • Blajger Konrad
  • Flor Aleksandr
  • Gobbi Luka
  • Grebke Tsbinden Katrin
  • Kerner Mattias
  • Kun Bernd
  • Peters Jens-Uve
  • Rudol'F Markus
RU2562066C2
KYNURENINE-3-MONOOXYGENASE INHIBITORS 2009
  • Vitjak Dzhon
  • Toledo-Sherman Letisia M.
  • Domingez Selija
  • Kurtnej Stiven Martin
  • Jarnol'D Kristofer Dzhon
  • De Agujar Pena Paula Kristina
  • Shill Andreas
  • Vinkler Dirk
RU2523448C2
PROTEOLYSIS MODULATORS AND RELATED USES 2019
  • Crew, Andrew P.
  • Hornberger, Keith R.
  • Wang, Jing
  • Dong, Hanqing
  • Berlin, Michael
  • Crews, Craig M.
RU2805511C2

RU 2 727 179 C2

Authors

Gofreto Delfin

Koltsevski Sabin

Plansher Zhan-Mark

Shtoll Teodor

Alm Remi

Dates

2020-07-21Published

2016-11-02Filed