PHARMACEUTICAL COMPOSITION BASED ON AN ACTIVE SUBSTANCE, AN INHIBITOR OF DIPEPTIDYL PEPTIDASE-4, FOR PREVENTING THE DEVELOPMENT AND TREATMENT OF TYPE 2 DIABETES MELLITUS Russian patent published in 2020 - IPC A61K31/439 C07D471/00 A61P3/10 

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to medicine and pharmaceutical industry, namely to compositions intended for oral administration in order to prevent developing and treating type 2 diabetes mellitus. Essence of the invention consists in the fact that the created pharmaceutical composition contains an active component of antihyperglycemic action – highly effective inhibitor of dipeptidyl peptidase-4 (DPP-4), exo-(2S)-3-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-azabicyclo[2.2.1]heptane-2-carbonitrile – substance I in form of pharmaceutically acceptable salt forms, excipients and carriers.

Mol. weight 337.

Compositions also include inactive components, on the one hand, preserving the effectiveness of the active substance, and on the other hand – allowing varying dosage, release and duration of action in the body.

EFFECT: provided immediate, prolonged and modified release of the active ingredient for treating type 2 diabetes mellitus.

13 cl, 20 ex, 16 tbl, 2 dwg