PREPARATION OF GLUCOKINASE ACTIVATOR FOR ORAL ADMINISTRATION AND METHOD FOR PREPARATION THEREOF Russian patent published in 2020 - IPC A61K9/14 A61K31/4155 A61K47/32 A61P3/10 

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to the field of pharmaceuticals and medicine. First invention is a solid dispersion for treating type I diabetes, type II diabetes, impaired glucose tolerance, fasting blood glucose and hyperglycemia disorders, which contains polymer carrier and activator of gluconase HMS5552, isotopic-labelled analogues or pharmaceutically acceptable salts,

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Group of inventions also relates to a composition, a tablet and a capsule comprising said solid dispersion, and use of said dispersions, compositions, tablets and capsules for preparing a drug for treating or preventing type I diabetes, type II diabetes, impaired glucose tolerance, fasting blood glucose and hyperglycemia.

EFFECT: group of inventions provides pH-dependent dissolution of the dispersion and dosage forms based thereon.

36 cl, 9 dwg, 14 tbl, 21 ex