METHOD OF PREDICTING THE EFFECTIVENESS OF PROLONGED SPECIFIC THERAPY IN PATIENTS WITH IDIOPATHIC PULMONARY HYPERTENSION AND INOPERABLE CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION Russian patent published in 2020 - IPC G01N33/68 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to cardiology and pulmonology, and aims at predicting the effectiveness of prolonged therapy in patients with idiopathic pulmonary hypertension and inoperable chronic thromboembolic pulmonary hypertension. Examination is carried out at the beginning of the therapy with determining the right ventricular end-diastolic volume (RV EDV) and NT-proBNP level and 12 months after the beginning of the repeated NT-proBNP level determination therapy. Effectiveness of the therapy is determined by the indicator of the level of NT-proBNP for 12 months in a combination with the RV EDV value at the beginning of therapy. If the level of NT-proBNP reaches < 30.4 pg/ml 12 months later in combination with RV EDV < 150.5 ml at the beginning of therapy, its effectiveness is predicted. If the values of NT-proBNP > 30.4 pg/ml 12 months after initiation of the therapy, or the level of NT-proBNP < 30.4 pg/ml in combination with the RV EDV value > 150.5 ml, the therapy is ineffective.

EFFECT: invention provides higher efficiency and accuracy of prediction.

1 cl, 4 ex, 1 dwg