SOLID FORMS OF ALPHA, OMEGA DISUBSTITUTED DIHYDROXY CYCLOPENTYL COMPOUND AND METHODS FOR PRODUCTION AND USE THEREOF Russian patent published in 2020 - IPC C07D333/28 A61K31/381 A61P27/06 

Abstract RU 2730520 C2

FIELD: chemical or physical processes.

SUBSTANCE: invention relates to crystalline form 7-[3α,5α-dihydroxy-2-(3α-hydroxy-5-(3-(2,5-dichlor)thienyl)-1E-pentenyl)cyclopentyl]-5Z-hepteneamide:

,

which is a hydrate (Form B), having powder X-ray diffraction diagram (Cu Kα, λ=1.54Å) with peaks of about 11.64, 19.57, 21.99, 22.74 and 25.06 degrees 2θ, as well as a method for production thereof.

EFFECT: disclosed are solid forms of alpha, omega disubstituted dihydroxycyclopentyl compound and methods for production and use thereof.

8 cl, 4 tbl, 7 ex, 8 dwg

Similar patents RU2730520C2

Title Year Author Number
HETEROARYLALKENYL DERIVATIVES OF CYCLOPENTANEHEPTAN(EN)OIC ACID 1998
  • Berk Robert M.
RU2217145C2
COMPOSITIONS AND METHODS FOR HAIR GROWTH STIMULATION 2010
  • Trogden Dzhon T.
  • Salamekh Adnan
  • Pudzhara Chetan P.
RU2567792C2
7-[3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-N-ETHYL-HEPT-5-ENEAMIDE (BIMATOPROST) IN CRYSTALLINE FORM II, METHODS OF THEREOF OBTAINING AND METHODS FOR APPLICATION THEREOF 2010
  • Embras Dzhiordzhi F.
  • Kejrami Kajomars
  • Vu Ke
RU2577546C2
(1S,2S,4R)-4-{4-[(1S)-2,3-DIHYDRO-1H-INDEN-1-YLAMINO]-7H-PYRROLO[2,3-d]PYRIMIDIN-7-YL}-2-HYDROXYCYCLOPENTYL)METHYL SULPHAMATE HYDROCHLORIDE 2010
  • Armitehjdzh Ian G.
  • Chopra Reenu
  • Kuper Martin Ian
  • Lehngston Mehriann
  • Lehngston Stefen P
  • Viskochil Stepan
RU2562245C2
STEROID COMPOUNDS (VARIANTS), PHARMACEUTICAL COMPOSITION, METHOD OF TREATMENT OF PATIENTS WITH NERVOUS DISORDERS (VARIANTS) AND METHOD OF ANESTHESIA INDUCTION IN ANIMAL 1995
  • Boldzhehr Majkl B.
  • Gi Kelvin U.
  • Lehn Nensi K.
  • Pehrdi Robert
  • Takhir Khasan
  • Jupehzehnaj Rehjvindra B.
RU2176248C2
NEW METHODS OF PROSTAGLANDIN AMIDES OBTAINING 2012
  • Khavashi Gabor
  • Kishsh Tibor
  • Khortobadi Iren
  • Kardosh Zhuzhanna
  • Laslofi Ishtvan
  • Bischof Zoltan
  • Bodish Adam
RU2618223C2
CRYSTALLINE FUMARATE SALT OF (S)-[3,4-DIFLUORO-2-(2-FLUORO-4-IODOPHENYLAMINO)PHENYL][3-HYDROXY-3-(PIPERIDINE-2-YL)AZETIDINE-1-YL]METHANONE 2016
  • Brown, Adrian St. Clair
RU2762181C2
ORGANIC COMPOUNDS 2019
  • Vanover, Kimberly
  • Li, Peng
  • Davis, Robert
  • Qiao, Yupu
RU2809023C2
CARDIOPROTECTIVE AGENT AND ITS COMPOSITION 1995
  • Al'Fred P. Spada
  • Sintia A. Fink
  • Majkl R. Majers
RU2166319C2
METHOD FOR PRODUCTION OF CRYSTAL FORM OF CALCOBUTROL A MODIFICATION 2017
  • Platzek Johannes
  • Trentmann Wilhelm
RU2786716C2

RU 2 730 520 C2

Authors

Vu Ke

Ambrus Giorgi

Dates

2020-08-24Published

2014-12-12Filed