NEW METHODS OF PROSTAGLANDIN AMIDES OBTAINING Russian patent published in 2017 - IPC C07C405/00 C07D207/46 C07D233/60 C07D307/935 

Abstract RU 2618223 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method for prostaglandin amides preparation by general formula (I)

compounds of general formula (V)

a method for preparation of compounds of general formula (IIA)

via an intermediate lactone triol of general formula (XIII)

.

EFFECT: activated carboxylic acid derivatives of the present invention can be easily purified by crystallization to remove impurities and may also be easily converted to the desired amide final product under mild reaction conditions with high yields.

14 cl, 12 dwg

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RU 2 618 223 C2

Authors

Khavashi Gabor

Kishsh Tibor

Khortobadi Iren

Kardosh Zhuzhanna

Laslofi Ishtvan

Bischof Zoltan

Bodish Adam

Dates

2017-05-03Published

2012-05-25Filed