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(19)

RU

(11)

2 577 546

(13)

C2

(51)

IPC

C07C405/00(2006-01-01)

A61K31/5575(2006-01-01)

A61P27/06(2006-01-01)

(21) (22)

Application

2012125185/04, 2010-11-19

(24)

Start date

2010-11-19

(22)

Actual filing date

2010-11-19

(45)

Published

2016-03-20

(72)

Inventor

Embras Dzhiordzhi F.Kejrami KajomarsVu Ke

(73)

Holder

Allergan, Ink.

7-[3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYL-PENT-1-ENYL)-CYCLOPENTYL]-N-ETHYL-HEPT-5-ENEAMIDE (BIMATOPROST) IN CRYSTALLINE FORM II, METHODS OF THEREOF OBTAINING AND METHODS FOR APPLICATION THEREOF Russian patent published in 2016 - IPC C07C405/00 A61K31/5575 A61P27/06 

Abstract RU 2577546 C2

FIELD: chemistry.

SUBSTANCE: invention relates to novel crystalline form of bimatoprost ((Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenyl-pent-1-enyl]-cyclopentyl]-N-ethyl-hept-5-eneamide), method for thereof obtaining, pharmaceutical composition, containing it, and method for treating ocular hypertension and glaucoma.

EFFECT: novel crystalline form of bimatoprost, possessing higher stability.

8 cl, 7 dwg, 6 tbl

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RU 2 577 546 C2

Authors

Embras Dzhiordzhi F.

Kejrami Kajomars

Vu Ke

Dates

2016-03-20—Published

2010-11-19—Filed

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