FIELD: biotechnology.
SUBSTANCE: invention relates to bispecific antibodies to human beta-amyloid and human transferrin receptor, and can be used in medicine.
EFFECT: obtained antibodies consisting of two pairs of light and two pairs of heavy chain antibody and heavy chain-conjugated Fab fragment with SEQ ID NO: 6–9, SEQ ID NO: 1–3, 10, SEQ ID NO: 11–13 or SEQ ID NO: 14–17, can be used for binding beta-amyloid and transferrin receptor.
7 cl, 10 tbl, 6 ex
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RU2784486C1 |
