FIELD: biochemistry.
SUBSTANCE: invention relates to an isolated antibody which specifically binds to a human tau protein, a method for production thereof, as well as to use thereof for treating a disease associated with tau protein. Also disclosed is an isolated nucleic acid encoding said antibody, as well as a host cell containing said nucleic acid. Invention also relates to a method of detecting neurofibrillar tangles, neuroypile sutures and/or dystrophic neurites, involving contacting a sample with said antibody.
EFFECT: invention provides effective treatment of diseases associated with tau protein.
51 cl, 30 tbl, 13 ex, 24 dwg
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