ANTIBODIES AGAINST TRYPTASE, THEIR COMPOSITIONS AND APPLICATIONS Russian patent published in 2022 - IPC C07K16/40 A61K39/395 C12N15/13 C12N15/63 

Abstract RU 2771485 C2

FIELD: biotechnology.

SUBSTANCE: antibodies that bind to human beta 1 tryptase and pharmaceutical compositions including them are proposed. Nucleic acids, expression vectors and host cells intended for the production of the specified antibodies are also proposed.

EFFECT: invention provides for binding to human beta 1 tryptase with high affinity and inhibiting tryptase activity in vivo.

72 cl, 32 dwg, 17 tbl, 6 ex

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RU 2 771 485 C2

Authors

Chen, Xiaocheng

Dennis, Mark

Jackman, Janet

Koerber, James, T.

Lu, Mason

Maun, Henry, R.

Rajapaksa, Kathila

Ramanujan, Saroja

Staton, Tracy

Wu, Lawren

Yi, Tangsheng

Dates

2022-05-04Published

2018-02-09Filed