FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to a method to produce an anti-C5 antibody or its antigen-binding fragment with a higher affinity at pH 7.4 than at pH 5.8.
EFFECT: invention makes it possible to effectively obtain anti-C5 antibodies.
10 cl, 9 ex, 11 tbl, 25 dwg
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