FIELD: biotechnology.
SUBSTANCE: present invention relates to a method of producing conditionally active proteins. Invention also discloses criteria for selecting source proteins for detection methods and formats of said proteins.
EFFECT: invention enables genetic engineering to produce therapeutic and diagnostic molecules of proteins which are more active under the abberant condition than under normal physiological condition.
19 cl, 1 dwg, 4 tbl, 9 ex
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Authors
Dates
2020-10-06—Published
2016-02-24—Filed