FIELD: biochemistry.
SUBSTANCE: invention relates to the field of biochemistry, in particular to a chimeric antigen receptor for binding with a tyrosine-kinase growth factor receptor. An expression vector, a genetically engineered cytotoxic cell, and a pharmaceutical composition are disclosed. A method for producing a chimeric antigen receptor and a method for the treatment of cancer are also disclosed.
EFFECT: invention allows for the effective treatment of a disease associated with a tyrosine-kinase growth factor receptor.
23 cl, 6 dwg, 3 tbl, 7 ex
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