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RU

(11)

2 736 184

(13)

C1

(51)

IPC

A61K31/4184(2006-01-01)

A61K33/06(2006-01-01)

A61K33/42(2006-01-01)

A61K9/28(2006-01-01)

A61K9/36(2006-01-01)

A61P1/04(2006-01-01)

(21) (22)

Application

2019117402, 2019-06-04

(24)

Start date

2019-06-04

(22)

Actual filing date

2019-06-04

(45)

Published

2020-11-12

(72)

Inventor

Petrov Vladimir IvanovichSpasov Aleksandr AlekseevichChernikov Maksim ValentinovichStepanova Eleonora FedorovnaShevchenko Aleksandr MikhajlovichOganova Marina AlbertovnaMorkovnik Anatolij Savelevich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Obrazovatelnoe Uchrezhdenie Vysshego Obrazovaniya Gosudarstvennyj Meditsinskij Universitet" Ministerstva Zdravookhraneniya Rossijskoj Federatsii

PHARMACEUTICAL COMPOSITION HAVING ANTIULCER ACTIVITY, AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2020 - IPC A61K31/4184 A61K33/06 A61K33/42 A61K9/28 A61K9/36 A61P1/04 

Abstract RU 2736184 C1

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, to chemical-pharmaceutical industry, namely to a pharmaceutical composition exhibiting anti-ulcerative activity in the form of a solid dosage form. Composition consists of a nucleus containing as an active compound dinitrate 9-diethylaminoethyl-2-phenyl-imidazo[1,2-a]benzimidazole and as auxiliary inert calcium substances dibasic phosphate, polyvinylpyrrolidone K 30, stearic acid salt coated with a polymer shell based on cellulose ether and titanium dioxide, characterized in that as auxiliary inert substances, the core additionally contains lactose monohydrate, corn starch, calcium stearate as the stearic acid salt, and the polymer coating additionally contains polyethylene glycol 6000, triacetin and lactose monohydrate. Group of inventions also relates to a method of producing a pharmaceutical composition.

EFFECT: group of inventions provides optimization of composition and technological process of obtaining tablets, optimal release characteristics of active principle, as well as stable storage for 3 years.

2 cl, 1 tbl, 3 ex

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RU 2 736 184 C1

Authors

Petrov Vladimir Ivanovich

Spasov Aleksandr Alekseevich

Chernikov Maksim Valentinovich

Stepanova Eleonora Fedorovna

Shevchenko Aleksandr Mikhajlovich

Oganova Marina Albertovna

Morkovnik Anatolij Savelevich

Dates

2020-11-12—Published

2019-06-04—Filed

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