PELLETISED DRUG SHOWING ANTIVIRAL AND INTERFERONOGENIC ACTION, AND METHOD FOR PREPARING IT Russian patent published in 2012 - IPC A61K31/44 A61K31/4425 A61K47/00 A61K9/30 A61J3/10 A61P31/12 

Abstract RU 2449792 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to pharmaceutical industry. A pelletised form of amison contains the active substance amison-N-methyl-4-benzylcarbamidopyridinium iodide, as an excipient - lactose, basic magnesium carbonate, or dibasic calcium phosphate, or pre-gelled starch, and also microcrystalline cellulose, as binding agents - saccharose and povidone, as an anti-cleavage agent - copolyvidone, as a desintegrant - crospovidone or sodium croscarmellose and as sliding agents - stearic acid, and/or a calcium stearate, and/or magnesium stearate. An amison pellet can be film-coated. The amison pellet is prepared by wet granulation.

EFFECT: amison pellets under the invention are characterised by high fracture and abrasion strength and have no cleavages.

6 cl, 1 tbl

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RU 2 449 792 C1

Authors

Ivanov Sergej Viktorovich

Batishcheva Irina Veniaminovna

Meshcherjakova Nina Ivanovna

Nesterenko Natalija Alekseevna

Smirnova Elena Nikolaevna

Spitsyna Ljudmila Evgen'Evna

Telepina Natalija Alekseevna

Dates

2012-05-10Published

2010-08-27Filed