NEW FORM OF IL33, MUTATED FORMS OF IL33, ANTIBODIES, ANALYZES AND METHODS OF USING THEM Russian patent published in 2020 - IPC C07K16/24 A61K39/395 A61P29/00 A61P37/08 

Abstract RU 2736299 C2

FIELD: biochemistry.

SUBSTANCE: invention relates to an isolated antibody or antigen-binding fragment thereof specifically bound with IL-33 protein in a reduced form, a method for production thereof, as well as to use thereof for treating or preventing an inflammatory condition. Also disclosed is a polynucleotide encoding said antibody or fragment thereof, as well as a vector and a cell thereof.

EFFECT: invention enables effective treatment of the inflammatory condition.

24 cl, 58 dwg, 39 tbl, 12 ex

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RU 2 736 299 C2

Authors

Koen Emma S

Louv Devid K

Batler Robin

Skott Ian K

Vusden Ketrin A

Strejn Martin D

Karmen Sara

Ingland Elizabet Kh

Kemp Bendzhamin P

Riz Devid Dzh.

Ouverd-Sejer Ketrin L

Mastelin Tomas M

Sliman Mettyu

Khauslej Kirsti

Dates

2020-11-13Published

2016-03-30Filed