FIELD: biotechnology.
SUBSTANCE: described is a polynucleotide coding ORF15 isoform of GTPase of retinitis pigmentosa (RPGRORF15), containing a nucleotide sequence which is codon-optimized to increase accuracy of sequence replication, where the nucleotide sequence comprises a nucleotide sequence encoding an amino acid sequence which has at least 80 % identity with SEQ ID NO: 1.
EFFECT: invention extends the range of products for treating or preventing retinitis pigmentosa.
48 cl, 13 dwg, 5 ex
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