HUMAN EMBRYONIC RHABDOMYOSARCOMA CELL LINE 862 RMSAR KDD Russian patent published in 2020 - IPC C12N5/07 

Abstract RU 2737248 C1

FIELD: biotechnology.

SUBSTANCE: invention refers to biotechnology, namely to production of cell lines used for cell technologies in medicine. Obtained new human embryonic rhabdomyosarcoma cell line 862 RMSar KDD exhibits stable culture and morphological characteristics, is stored in Specialized collection of vertebrate cell cultures of Russian collection of cell cultures under registration number RKKK (P) 791D. Cell line is characterized by expression of antigens of the main histocompatibility complex of I and II classes, overexpression of cancer-testicular genes GAGE, PASD1, PRAME, production of chemokine CCL2.

EFFECT: can be used to create biomedical cell products, cell models, to test activity of various pharmaceutical preparations, create diagnostic kits and test systems in order to develop new therapeutic approaches and drugs.

1 cl, 3 ex

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RU 2 737 248 C1

Authors

Baldueva Irina Aleksandrovna

Danilova Anna Borisovna

Avdonkina Natalya Aleksandrovna

Nekhaeva Tatyana Leonidovna

Gafton Georgij Ivanovich

Belyaev Aleksej Mikhajlovich

Dates

2020-11-26Published

2020-04-28Filed