FIELD: biotechnology; medicine.
SUBSTANCE: invention refers to biotechnology, namely to production of cell lines used for cell technologies in medicine. Obtained new cell line of synovial human sarcoma 716 SS MNV has stable culture and morphological characteristics, is stored in Specialized collection of vertebrate cell cultures of Russian collection of cell cultures under registration number RKKK (P) 790D. Cell line is characterized by the expression of antigens of the main histocompatibility complex I class, expression of cancer-testicular antigens MAGE, BAGE, GAGE, NY-ESO-1, PRAME, used to create biomedical anti-tumor cell products, which enables higher clinical effectiveness and longer life in treating synovial sarcoma. Besides, the obtained new cell line can be used for testing activity of various pharmaceutical preparations, creation of diagnostic kits and test systems for development of new therapeutic approaches and medical products.
EFFECT: can be used to create biomedical cell products, cell models, to test activity of various pharmaceutical preparations, create diagnostic kits and test systems in order to develop new therapeutic approaches and drugs.
1 cl
| Title | Year | Author | Number |
|---|---|---|---|
| HUMAN ALVEOLAR SARCOMA CELL LINE 9927 AIS SIO | 2022 |
|
RU2796356C1 |
| CELL PRODUCT FOR LOADING AND ACTIVATION OF HUMAN DENDRITE CELLS | 2019 |
|
RU2714208C1 |
| OSTEOGENIC HUMAN SARCOMA CELL LINE 793 OSSAR RVV | 2019 |
|
RU2722867C1 |
| APPLICATION OF CELL LINE OF RC291C CLEAR CELL ADENOCARCINOMA | 2018 |
|
RU2673729C1 |
| MOUSE SPINDLE CELL SARCOMA CELL LINE 164 MSar FE | 2023 |
|
RU2796351C1 |
| HUMAN EMBRYONIC RHABDOMYOSARCOMA CELL LINE 862 RMSAR KDD | 2020 |
|
RU2737248C1 |
| HUMAN BLADDER CANCER CELL LINE 198 BLCAN RLA | 2019 |
|
RU2733230C1 |
| HUMAN BLADDER CANCER CELL LINE 190 BICAN KAG | 2021 |
|
RU2779948C1 |
| APPLICATION OF HUMAN SKIN MELANOMA CELL LINE 388mel | 2018 |
|
RU2675541C1 |
| HUMAN BLADDER CANCER CELL LINE 587 BLCAN TVV | 2020 |
|
RU2742244C1 |
