FIELD: medicine.
SUBSTANCE: invention refers to experimental medicine. Method for simulating diet-induced metabolic syndrome in laboratory animals involves using a high-fat and high-carbohydrate diet, characterized in that animals receive ration for 12 weeks, containing standard fodder (specific weight 66 %) with addition of animal fat (melted lard, specific weight 17 %), fructose (specific weight 17 %), cholesterol (specific gravity 0.1 %), and consuming 20 % solution of fructose instead of drinking water.
EFFECT: technical result is a model of metabolic syndrome, adequately reflecting the main features of metabolic disorders developing in the given syndrome.
1 cl, 5 dwg
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR STEP-BY-STEP MODELING OF NONALCOHOLIC FATTY PANCREATIC DISEASE IN RATS | 2021 |
|
RU2770555C1 |
| COMPOSITION FOR PREVENTION AND TREATMENT OF OBESITY AND ASSOCIATED METABOLIC DISORDERS | 2020 |
|
RU2763348C2 |
| COMPOSITION FOR METABOLIC SYNDROME CORRECTION | 2016 |
|
RU2616241C1 |
| (2S)-3-(4-{2-[4-(2-{[(1R,4AR,7S)-7-ETHYNYL-1,4A,7-TRIMETHYL-1,2,3,4,4A,4B,5,6,7,8,10,10A-DODECAHYDROPHENANTHREN-1-YL]FORMAMIDO}ETHOXY)PHENYL]ETHOXY}PHENYL)-2-ETHOXY-PROPANOIC ACID FOR THERAPY AND PREVENTION OF METABOLIC SYNDROME | 2023 |
|
RU2813464C1 |
| METHOD OF CORRECTING METABOLIC SYNDROME UNDER EXPERIMENTAL CONDITION | 2022 |
|
RU2806875C1 |
| LIPID-CORRECTING AGENT OF SEAWEED | 2021 |
|
RU2767908C1 |
| HEPATOPROTECTIVE EFFECT OF LOW MOLECULAR WEIGHT MIMETICS NGF | 2022 |
|
RU2790828C1 |
| TREATMENT OF LIVER, BILE DUCT AND PANCREATIC DISORDERS | 2017 |
|
RU2740913C2 |
| METHOD OF SIMULATING MULTIPLE ORGAN PATHOLOGY IN RATS | 2011 |
|
RU2453002C1 |
| MEANS FOR NON-ALCOHOLIC FATTY LIVER DISEASE TREATMENT AND PREVENTION | 2016 |
|
RU2644282C2 |
