MEDICINES BASED ON LANTIONINE SYNTHETASE OF C-LIKE PROTEIN 2 Russian patent published in 2021 - IPC C07D403/12 C07D403/14 C07D401/14 A61K31/4184 A61K31/4439 A61K31/496 A61P31/12 A61P29/00 

FIELD: chemistry; medicine; pharmaceuticals.

SUBSTANCE: invention relates to a compound of formula:

or a pharmaceutically acceptable salt thereof, wherein Q is piperazine-1,4-diiyl; each of A₁ and A₁' independently represents N or CR⁶; each of A₂ and A₂' is CR⁷; A₃ is NR⁸; A₃' is NR⁸ or O; each of A₄ and A₄' is N; each of A₅ and A₅' is CR¹⁰; each of A₆ and A₆' is CR¹¹; and each of R¹, R^1', R², R^2', R³, R^3', R⁴, R^4', R⁶, R⁷, R⁸, R⁹, R¹⁰ and R¹¹ is hydrogen, provided that the compound is not

or a pharmaceutically acceptable salt thereof.

EFFECT: obtaining novel compounds aimed at a pathway of lanthionine synthetase of C-like protein 2, which can be used in medicine for treating a number of conditions, including an infectious disease, an autoimmune disease, diabetes and a chronic inflammatory disease.

22 cl, 40 dwg, 24 ex